PRPH (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PRPH full-length ORF ( NP_006253.2, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSHHPSGLRAGFSSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSELDKSSAHSY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
80.1
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PRPH
Entrez GeneID
5630GeneBank Accession#
NM_006262.3Protein Accession#
NP_006253.2Gene Name
PRPH
Gene Alias
NEF4, PRPH1
Gene Description
peripherin
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq
Other Designations
neurofilament 4 (57kD)
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Interactome
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Pathway
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Disease
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Publication Reference
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Peripherin partially localizes in Bunina bodies in amyotrophic lateral sclerosis.
Mizuno Y, Fujita Y, Takatama M, Okamoto K.
Journal of the Neurological Sciences 2011 Mar; 302(1-2):14.
Application:Func, Antibody.
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Peripherin partially localizes in Bunina bodies in amyotrophic lateral sclerosis.
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