MAPK8 purified MaxPab rabbit polyclonal antibody (D01P)

Catalog # H00005599-D01P

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Size:100 ug
Price: USD $ 376.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Tissue lysate)
Application

Western Blot (Tissue lysate)

MAPK8 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAPK8 expression in mouse lung.

Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

MAPK8 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAPK8 expression in HeLa.

Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of MAPK8 expression in transfected 293T cell line (H00005599-T01) by MAPK8 MaxPab polyclonal antibody.

Lane 1: MAPK8 transfected lysate(48.30 KDa).
Lane 2: Non-transfected lysate.

<em>In situ</em> Proximity Ligation Assay (Cell)
Application

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between MAPK8 and FASLG. HeLa cells were stained with anti-MAPK8 rabbit purified polyclonal 1:1200 and anti-FASLG mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Immunofluorescence
Application

Immunofluorescence

Immunofluorescence of purified MaxPab antibody to MAPK8 on HeLa cell. [antibody concentration 10 ug/ml]

  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against a full-length human MAPK8 protein.MaxPab Polyclonal Antibody,MaxPab Polyclonal Antibodies,MaxPab,DNA Immune,DNA Immunization,Immune Technology

    Immunogen

    MAPK8 (NP_620637.1, 1 a.a. ~ 427 a.a) full-length human protein.

    Sequence

    MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR

    Host

    Rabbit

    Reactivity

    Human, Mouse

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Tissue lysate)

    MAPK8 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAPK8 expression in mouse lung.

    Western Blot (Cell lysate)

    MAPK8 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAPK8 expression in HeLa.

    Western Blot (Transfected lysate)

    Western Blot analysis of MAPK8 expression in transfected 293T cell line (H00005599-T01) by MAPK8 MaxPab polyclonal antibody.

    Lane 1: MAPK8 transfected lysate(48.30 KDa).
    Lane 2: Non-transfected lysate.

    In situ Proximity Ligation Assay (Cell)

    Proximity Ligation Analysis of protein-protein interactions between MAPK8 and FASLG. HeLa cells were stained with anti-MAPK8 rabbit purified polyclonal 1:1200 and anti-FASLG mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

    Immunofluorescence

    Immunofluorescence of purified MaxPab antibody to MAPK8 on HeLa cell. [antibody concentration 10 ug/ml]
  • Gene Info — MAPK8

    Entrez GeneID

    5599

    GeneBank Accession#

    NM_139049

    Protein Accession#

    NP_620637.1

    Gene Name

    MAPK8

    Gene Alias

    JNK, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1

    Gene Description

    mitogen-activated protein kinase 8

    Omim ID

    601158

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

    Other Designations

    JNK1 alpha protein kinase|JNK1 beta protein kinase|JUN N-terminal kinase|OTTHUMP00000019552|OTTHUMP00000019555|OTTHUMP00000019556|OTTHUMP00000019558|c-Jun N-terminal kinase 1|mitogen-activated protein kinase 8 isoform JNK1 alpha1|mitogen-activated protein

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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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