PARK7 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PARK7 protein.
Immunogen
PARK7 (NP_009193.2, 1 a.a. ~ 189 a.a) full-length human protein.
Sequence
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
PARK7 MaxPab polyclonal antibody. Western Blot analysis of PARK7 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of PARK7 expression in transfected 293T cell line (H00011315-T01) by PARK7 MaxPab polyclonal antibody.
Lane 1: PARK7 transfected lysate(20.79 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PARK7
Entrez GeneID
11315GeneBank Accession#
NM_007262.3Protein Accession#
NP_009193.2Gene Name
PARK7
Gene Alias
DJ-1, DJ1, FLJ27376, FLJ34360, FLJ92274
Gene Description
Parkinson disease (autosomal recessive, early onset) 7
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000001348|OTTHUMP00000001349|OTTHUMP00000001350|OTTHUMP00000001351|Parkinson disease protein 7|oncogene DJ1|protein DJ-1
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Interactome
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Disease
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Publication Reference
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Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands.
Donadio E, Giusti L, Cetani F, Da Valle Y, Ciregia F, Giannaccini G, Pardi E, Saponaro F, Torregrossa L, Basolo F, Marcocci C, Lucacchini A.
Proteome Science 2011 Jun; 9(1):29.
Application:WB-Ti, Human, Parathyroid adenoma.
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Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands.
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