PARK7 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of PARK7 in 293 cells and mouse brain lysates with PARK7 polyclonal antibody (Cat # PAB12080).
Immunofluorescence
Immunofluorescence staining of PARK7 on human cortex with PARK7 polyclonal antibody at concentration (Cat # PAB12080).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PARK7.
Immunogen
A synthetic peptide corresponding to amino acids 150-189 of human PARK7.
Host
Rabbit
Reactivity
Bovine, Chicken, Hamster, Human, Mouse, Rat, Zebra fish
Specificity
This antibody is specific to DJ-1.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunocytochemistry (1:500)
Immunoprecipitation (1:200)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
No additive
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot analysis of PARK7 in 293 cells and mouse brain lysates with PARK7 polyclonal antibody (Cat # PAB12080).Immunocytochemistry
Immunofluorescence
Immunofluorescence staining of PARK7 on human cortex with PARK7 polyclonal antibody at concentration (Cat # PAB12080).Immunoprecipitation
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Gene Info — PARK7
Entrez GeneID
11315Gene Name
PARK7
Gene Alias
DJ-1, DJ1, FLJ27376, FLJ34360, FLJ92274
Gene Description
Parkinson disease (autosomal recessive, early onset) 7
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000001348|OTTHUMP00000001349|OTTHUMP00000001350|OTTHUMP00000001351|Parkinson disease protein 7|oncogene DJ1|protein DJ-1
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Interactome
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Disease
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Publication Reference
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Identification of novel proteins associated with both alpha-synuclein and DJ-1.
Jin J, Li GJ, Davis J, Zhu D, Wang Y, Pan C, Zhang J.
Molecular & Cellular Proteomics 2007 May; 6(5):845.
Application：IF, IP, WB, Rat, Rat mesencephalic neuronal cell line.
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Identification of novel proteins associated with both alpha-synuclein and DJ-1.
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