PARK7 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PARK7.
Immunogen
A synthetic peptide corresponding to human PARK7.
Sequence
C-AAQVKAPLVLKD
Host
Goat
Theoretical MW (kDa)
19.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
PARK7 polyclonal antibody (Cat # PAB6353) staining (1 ug/mL) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PARK7
Entrez GeneID
11315Protein Accession#
NP_009193Gene Name
PARK7
Gene Alias
DJ-1, DJ1, FLJ27376, FLJ34360, FLJ92274
Gene Description
Parkinson disease (autosomal recessive, early onset) 7
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000001348|OTTHUMP00000001349|OTTHUMP00000001350|OTTHUMP00000001351|Parkinson disease protein 7|oncogene DJ1|protein DJ-1
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Interactome
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Disease
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Publication Reference
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Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
Willis D, Li KW, Zheng JQ, Chang JH, Smit A, Kelly T, Merianda TT, Sylvester J, van Minnen J, Twiss JL.
The Journal of Neuroscience 2005 Jan; 25(4):778.
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Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
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