ISL1 recombinant monoclonal antibody, clone R05-2C3
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: rat brain lysates with ISL1 recombinant monoclonal antibody, clone R05-2C3 (Cat # RAB02159).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ISL1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human ISL1.
Theoretical MW (kDa)
Calculated MW: 39 kD
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: rat brain lysates with ISL1 recombinant monoclonal antibody, clone R05-2C3 (Cat # RAB02159).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — ISL1
Entrez GeneID
3670Protein Accession#
P61371Gene Name
ISL1
Gene Alias
Isl-1
Gene Description
ISL LIM homeobox 1
Omim ID
600366Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq
Other Designations
ISL1 transcription factor, LIM/homeodomain|islet-1
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Interactome
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Disease
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