PIK3R3/PIK3R1/PIK3R2 recombinant monoclonal antibody, clone PI3KY458-1A11
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More Files
- More Functions
Western Blot
Western blot analysis of NIH3T3 cell extract, untreated or treated with UV using 0.5 ug/mL Phospho-PI3Kinase p85 (Tyr458)/p55 (Tyr199) antibody PI3KY458-1A11.
Flow Cytometry
Flow cytometric analysis of NIH3T3 cells secondary antibody only negative control (blue) or 0.1 ug/mL of isotype control orange) or treated with imatinib (red) or with pervanadate (green) using Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) antibody PI3KY458-1A11 at 0.1 ug/mL.
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Specifications
Product Description
Rabbit recombinant monoclonal antibody raised against human PIK3R3 | PIK3R1 | PIK3R2.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr458 of human phospho PI3K p85
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.02% Sodium azide, 50% Glycerol, 0.1% BSA
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of NIH3T3 cell extract, untreated or treated with UV using 0.5 ug/mL Phospho-PI3Kinase p85 (Tyr458)/p55 (Tyr199) antibody PI3KY458-1A11.Flow Cytometry
Flow cytometric analysis of NIH3T3 cells secondary antibody only negative control (blue) or 0.1 ug/mL of isotype control orange) or treated with imatinib (red) or with pervanadate (green) using Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) antibody PI3KY458-1A11 at 0.1 ug/mL. -
Gene Info — PIK3R1
Entrez GeneID
5295Protein Accession#
Q92569 | P27986 | O00459Gene Name
PIK3R1
Gene Alias
GRB1, p85, p85-ALPHA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Omim ID
171833Gene Ontology
HyperlinkGene Summary
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)|phosphoinositide-3-ki
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Gene Info — PIK3R2
Entrez GeneID
5296Protein Accession#
Q92569 | P27986 | O00459Gene Name
PIK3R2
Gene Alias
P85B, p85, p85-BETA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Omim ID
603157Gene Ontology
HyperlinkGene Summary
O
Other Designations
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)|phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
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Gene Info — PIK3R3
Entrez GeneID
8503Protein Accession#
Q92569 | P27986 | O00459Gene Name
PIK3R3
Gene Alias
DKFZp686P05226, FLJ41892, p55, p55-GAMMA
Gene Description
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Omim ID
606076Gene Ontology
HyperlinkGene Summary
O
Other Designations
100% homology to SWISS-PROT Q92569|OTTHUMP00000009783|OTTHUMP00000009786|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subun
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Interactomes
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Pathways
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Diseases
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