Products

Western Blot

Immunohistochemistry

Immunocytochemical staining of mouse tissue using CDK9 polyclonal antibody (Cat # PAB9941).
The staining shows the location of CDK9 protein in developing mouse tissue. Arrows indicate areas of high expression.
Panel A : Peroxidase-DAB immunostaining of CDK9 protein in the developing mouse brain in the differentiated region of the medulla oblongata just below the fourth ventricle.
Similar staining is shown in Panel B in the dorsal root ganglia.
Panel C : Fluorescein immunofluorescence of CDK9 in skeletal muscle.
Similar staining is shown in Panel D in cardiac muscle.

Immunoprecipitation

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

1025

Protein Accession#

P50750;NP_001252

Gene Name

CDK9

Gene Alias

C-2k, CDC2L4, CTK1, PITALRE, TAK

Gene Description

cyclin-dependent kinase 9

Omim ID

603251

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq

Other Designations

CDC2-related kinase|OTTHUMP00000022198|cell division protein kinase 9|serine/threonine protein kinase PITALRE