PPARG polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPARG.
Immunogen
A synthetic peptide corresponding to human PPARG.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot analysis of extract from mouse adipose tissue, using PPARG polyclonal antibody (Cat # PAB8500) . -
Gene Info — PPARG
Entrez GeneID
5468Gene Name
PPARG
Gene Alias
CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
Gene Description
peroxisome proliferator-activated receptor gamma
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000185030|OTTHUMP00000185033|OTTHUMP00000185037|PPAR gamma|nuclear receptor subfamily 1 group C member 3|peroxisome proliferative activated receptor gamma|peroxisome proliferative activated receptor, gamma|peroxisome proliferator activated recept
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Interactome
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Pathway
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Disease
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Publication Reference
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PPAR-gamma: a thrifty transcription factor.
Auwerx J, Cock TA, Knouff C.
Nuclear Receptor Signaling 2003 Jun; 1:e006.
Application:IHC, WB, Human, Mammalian cells.
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PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al..
Molecular Cell 1999 Oct; 4(4):597.
Application:IHC-P, Mouse, Maternal decidua, Placenta.
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PPAR-gamma: a thrifty transcription factor.
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