PPARG monoclonal antibody, clone 8D1H8F4
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More Files
- More Functions
Western Blot
Western blot analysis using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) against truncated PPARG recombinant protein (Lane 1) and K-562 cell lysate (Lane 2).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human carcinoma and normal tissue, showing nuclear localization using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) with DAB staining.
Immunofluorescence
Confocal analysis of A-431 cells using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) showing nuclear staining.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant PPARG.
Immunogen
Recombinant protein corresponding to truncated human PPARG.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:2000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000)
Immunohistochemistry (Frozen sections) (1:500-1:2000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot analysis using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) against truncated PPARG recombinant protein (Lane 1) and K-562 cell lysate (Lane 2).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human carcinoma and normal tissue, showing nuclear localization using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) with DAB staining.Immunohistochemistry (Frozen sections)
Immunofluorescence
Confocal analysis of A-431 cells using PPARG monoclonal antibody, clone 8D1H8F4 (Cat # MAB8316) showing nuclear staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PPARG
Entrez GeneID
5468Gene Name
PPARG
Gene Alias
CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
Gene Description
peroxisome proliferator-activated receptor gamma
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000185030|OTTHUMP00000185033|OTTHUMP00000185037|PPAR gamma|nuclear receptor subfamily 1 group C member 3|peroxisome proliferative activated receptor gamma|peroxisome proliferative activated receptor, gamma|peroxisome proliferator activated recept
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Interactome
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Pathway
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Disease
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Publication Reference
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Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones.
Weng JR, Chen CY, Pinzone JJ, Ringel MD, Chen CS.
Endocrine-Related Cancer 2006 Jun; 13(2):401.
Application：WB-Ce, Human, LNCaP, PC-3 cells.
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Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis.
Yang HC, Ma LJ, Ma J, Fogo AB.
Kidney International 2006 May; 69(10):1756.
Application：IHC-P, IS, Rat, Kidneys.
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Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells.
Ahdjoudj S, Kaabeche K, Holy X, Fromigue O, Modrowski D, Zerath E, Marie PJ.
Experimental Cell Research 2005 Feb; 303(1):138.
Application：IP, WB, Rat, Bone marrow stromal cells.
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Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones.
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