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STAT1 polyclonal antibody

  • Catalog # : PAB8012
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial synthetic peptide of human STAT1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 364-378 of human STAT1.
  • Sequence:
  • FDKDVNERNTVKGFR
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rabbit, Rat
  • Form:
  • Lyophilized
  • Purification:
  • Immunogen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.1-0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.2 mg Na2HPO4, 0.9 mg NaCl (0.05 mg Thimerosal, 0.05 mg sodium azide, 5 mg BSA).
  • Storage Instruction:
  • Store at -20°C.
    After reconstitution with 0.2 mL of distilled water and concentration will be 500 ug/mL, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and Thimerosol: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease.
    Chapgier A, Boisson-Dupuis S, Jouanguy E, Vogt G, Feinberg J, Prochnicka-Chalufour A, Casrouge A, Yang K, Soudais C, Fieschi C, Santos OF, Bustamante J, Picard C, de Beaucoudrey L, Emile JF, Arkwright PD, Schreiber RD, Rolinck-Werninghaus C, Rosen-Wolff A, Magdorf K, Roesler J, Casanova JL.PLoS Genet. 2006 Aug 18;2(8):e131.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of human colon cancer lysate. Using STAT1 polyclonal antibody (Cat # PAB8012) .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6772
  • Gene Name:
  • STAT1
  • Gene Alias:
  • DKFZp686B04100,ISGF-3,STAT91
  • Gene Description:
  • signal transducer and activator of transcription 1, 91kDa
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000165047,signal transducer and activator of transcription 1,signal transducer and activator of transcription-1,transcription factor ISGF-3 components p91/p84
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