STAT1 recombinant monoclonal antibody, clone Stat1Y701-3E6 (PE)
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More Files
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Flow Cytometry
Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNα IL-4 and pervanadate (green) using phospho-Stat1 (Tyr701) antibody Stat1Y701-3E6 PE conjugate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human STAT1.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr701 of human phospho Stat1
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNα IL-4 and pervanadate (green) using phospho-Stat1 (Tyr701) antibody Stat1Y701-3E6 PE conjugate. -
Gene Info — STAT1
Entrez GeneID
6772Protein Accession#
P42224Gene Name
STAT1
Gene Alias
DKFZp686B04100, ISGF-3, STAT91
Gene Description
signal transducer and activator of transcription 1, 91kDa
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000165047|signal transducer and activator of transcription 1|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91/p84
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Interactome
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