CSTB polyclonal antibody

Catalog # PAB30012

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Size:100 uL
Price: USD $ 531.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of transfected 293T cell lysate with CSTB polyclonal antibody (Cat # PAB30012) at 0.25 ug/mL working concentration.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with CSTB polyclonal antibody (Cat # PAB30012) at 4-8 ug/mL working concentration.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of human CSTB.

    Immunogen

    A synthetic peptide corresponding to internal region of human CSTB.

    Sequence

    AGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF

    Host

    Rabbit

    Theoretical MW (kDa)

    11

    Reactivity

    Human

    Form

    Liquid

    Purification

    Affinity purification

    Recommend Usage

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
    Western Blot (0.25 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS (2% sucrose, 0.09% sodium azide).

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot analysis of transfected 293T cell lysate with CSTB polyclonal antibody (Cat # PAB30012) at 0.25 ug/mL working concentration.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with CSTB polyclonal antibody (Cat # PAB30012) at 4-8 ug/mL working concentration.
  • Gene Info — CSTB

    Entrez GeneID

    1476

    GeneBank Accession#

    NM_000100

    Protein Accession#

    NP_000091;P04080

    Gene Name

    CSTB

    Gene Alias

    CST6, EPM1, PME, STFB

    Gene Description

    cystatin B (stefin B)

    Omim ID

    254800 601145

    Gene Ontology

    Hyperlink

    Gene Summary

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq

    Other Designations

    CPI-B|cystatin B|liver thiol proteinase inhibitor|stefin B

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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