RAD21 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with RAD21 polyclonal antibody (Cat # PAB21266) shows strong nuclear positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with RAD21 polyclonal antibody (Cat # PAB21266) at 1-4 ug/mL dilution shows positivity in nuclei but not nucleoli.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RAD21.
Immunogen
Recombinant protein corresponding to amino acids of human RAD21.
Sequence
KLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVEL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with RAD21 polyclonal antibody (Cat # PAB21266) shows strong nuclear positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with RAD21 polyclonal antibody (Cat # PAB21266) at 1-4 ug/mL dilution shows positivity in nuclei but not nucleoli. -
Gene Info — RAD21
Entrez GeneID
5885Protein Accession#
O60216Gene Name
RAD21
Gene Alias
FLJ25655, FLJ40596, HR21, HRAD21, KIAA0078, MCD1, NXP1, SCC1, hHR21
Gene Description
RAD21 homolog (S. pombe)
Omim ID
606462Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq
Other Designations
RAD21 homolog|nuclear matrix protein 1|protein involved in DNA double-strand break repair
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com