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Last updated: 2016/12/11
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LAT polyclonal antibody

  • Catalog # : PAB17296
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LAT.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding serine 363 of human LAT.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody detects endogenous levels of total LAT protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    ELISA (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from A-549 cells, using LAT polyclonal antibody (Cat # PAB17296).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • LAT
  • Gene Alias:
  • LAT1,pp36
  • Gene Description:
  • linker for activation of T cells
  • Gene Summary:
  • The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • 36 kDa phospho-tyrosine adaptor protein
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