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Last updated: 2016/12/4
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MTOR polyclonal antibody

  • Catalog # : PAB12715
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MTOR.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human MTOR.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 290
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody only recognizes ~290 KDa of human MTOR.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Immunoprecipitation
  • The cell lysate derived from MCF-7 was immuno-precipitated by MTOR polyclonal antibody (Cat # PAB12715), resolved onto 7.5% SDS-PAGE, transferred onto NC membrane, then immuno-blotted by MTOR polyclonal antibody (Cat # PAB12715) at 1 : 500.
    An immunoreactive band around ~290 kDa was observed (lane 1). Lane 2 is a negative control.
  • ELISA
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2475
  • Gene Name:
  • MTOR
  • Gene Alias:
  • FRAP,FRAP1,FRAP2,RAFT1,RAPT1
  • Gene Description:
  • mechanistic target of rapamycin
  • Gene Summary:
  • The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
  • Other Designations:
  • FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein 1
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