MTOR recombinant monoclonal antibody, clone mTORS2448-E11
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of NIH3T3 cells secondary antibody only negative control (blue) or 0.01 ug/mL of isotype control (orange) or untreated (red) or treated with PDGF (green) using Phospho-mTOR (Ser2448) antibody mTORS2448-E11 at 0.01 ug/mL.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MTOR.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.02% Sodium azide, 50% Glycerol, 0.1% BSA
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of NIH3T3 cells secondary antibody only negative control (blue) or 0.01 ug/mL of isotype control (orange) or untreated (red) or treated with PDGF (green) using Phospho-mTOR (Ser2448) antibody mTORS2448-E11 at 0.01 ug/mL. -
Gene Info — MTOR
Entrez GeneID
2475Protein Accession#
P42345Gene Name
MTOR
Gene Alias
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Description
mechanistic target of rapamycin
Omim ID
601231Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
Other Designations
FK506 binding protein 12-rapamycin associated protein 1|FK506 binding protein 12-rapamycin associated protein 2|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1
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Interactome
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Pathway
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Disease
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