MTOR recombinant monoclonal antibody, clone mTORS2448-E11 (APC)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of A431 cells treated with phosphatase and unstained as negative control (blue) or treated with phosphatase (red) or EGF (green) and stained using Phospho-mTOR (Ser2448) APC conjugated antibody mTORS2448-E11.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MTOR.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% Sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of A431 cells treated with phosphatase and unstained as negative control (blue) or treated with phosphatase (red) or EGF (green) and stained using Phospho-mTOR (Ser2448) APC conjugated antibody mTORS2448-E11. -
Gene Info — MTOR
Entrez GeneID
2475Protein Accession#
P42345Gene Name
MTOR
Gene Alias
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Description
mechanistic target of rapamycin
Omim ID
601231Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
Other Designations
FK506 binding protein 12-rapamycin associated protein 1|FK506 binding protein 12-rapamycin associated protein 2|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1
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Interactome
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Pathway
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Disease
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