Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNΑ IL4 and pervanadate (green) using SRC (phospho Y416) monoclonal antibody (PE).
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq