SRC recombinant monoclonal antibody, clone SrcY416-C4
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of U937 cells secondary antibody only negative control (blue) or untreated (red) treated with IFNa IL4 and pervanadate (green) or treated + blocked with non-phospho-peptide (purple) or treated + blocked with phospho-peptide (brown) using 0.01 ug/mL Phospho-Src (Tyr416) antibody SrcY416-C4.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SRC.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr416 of human phospho Src
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.02% Sodium azide, 50% Glycerol, 0.1% BSA
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells secondary antibody only negative control (blue) or untreated (red) treated with IFNa IL4 and pervanadate (green) or treated + blocked with non-phospho-peptide (purple) or treated + blocked with phospho-peptide (brown) using 0.01 ug/mL Phospho-Src (Tyr416) antibody SrcY416-C4. -
Gene Info — SRC
Entrez GeneID
6714Protein Accession#
P12931Gene Name
SRC
Gene Alias
ASV, SRC1, c-SRC, p60-Src
Gene Description
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Omim ID
190090Gene Ontology
HyperlinkGene Summary
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000174476|OTTHUMP00000174477|proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1
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Interactome
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Pathway
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Disease
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