SRC recombinant monoclonal antibody, clone SrcY416-C4 (APC)
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SRC.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr416 of human phospho Src
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained and untreated (red) or treated with IFNa IL4 and pervanadate (green) using Phospho-Src (Tyr416) antibody SrcY416-C4 APC conjugate. -
Gene Info — SRC
Entrez GeneID
6714Protein Accession#
P12931Gene Name
SRC
Gene Alias
ASV, SRC1, c-SRC, p60-Src
Gene Description
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Omim ID
190090Gene Ontology
HyperlinkGene Summary
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000174476|OTTHUMP00000174477|proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1
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Interactome
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Pathway
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Disease
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