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BCL2 monoclonal antibody, clone BCL2/782

  • Catalog # : MAB13418
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human BCL2.
  • Immunogen:
  • Recombinant protein corresponding to full length human BCL2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 25-26
  • Reactivity:
  • Human
  • Specificity:
  • This monoclonal antibody shows no cross-reaction with Bcl-x or Bax protein.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil (A) and human melanoma (B) with BCL2 monoclonal antibody, clone BCL2/782 (Cat # MAB13418).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 596
  • Gene Name:
  • BCL2
  • Gene Alias:
  • Bcl-2
  • Gene Description:
  • B-cell CLL/lymphoma 2
  • Gene Summary:
  • This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq
  • Other Designations:
  • B-cell lymphoma protein 2,OTTHUMP00000163680
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