TNFRSF21 monoclonal antibody (M56), clone 8F5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFRSF21.
Immunogen
TNFRSF21 (AAH17730.1, 89 a.a. ~ 170 a.a) partial recombinant protein.
Sequence
SSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — TNFRSF21
Entrez GeneID
27242GeneBank Accession#
BC017730.1Protein Accession#
AAH17730.1Gene Name
TNFRSF21
Gene Alias
BM-018, DR6, MGC31965
Gene Description
tumor necrosis factor receptor superfamily, member 21
Omim ID
605732Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq
Other Designations
OTTHUMP00000016561|OTTHUMP00000039915|TNFR-related death receptor 6|death receptor 6
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Interactome
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