TNFRSF21 polyclonal antibody
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More Files
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Western Blot (Transfected lysate)
Immunodetection of transfected human TNFRSF21 in HEK 293 cells using TNFRSF21 polyclonal antibody (Cat # PAB13779). Asterisks (*) represent N-glycosylated forms and arrow shows unglycosylated form of TNFRSF21.
Immunocytochemistry
Immunocytochemical analysis of transfected human TNFRSF21 in HEK 293 cells using TNFRSF21 polyclonal antibody (Cat # PAB13779). Confocal microscopy shows membrane localization of TNFRSF21 (nuclei stained was with anti-DRAQ5).
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TNFRSF21.
Immunogen
Recombinant protein corresponding to amino acids 372-665 of human TNFRSF21.
Host
Rabbit
Reactivity
Human
Specificity
Recognizes human DR6.
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
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Applications
Western Blot (Transfected lysate)
Immunodetection of transfected human TNFRSF21 in HEK 293 cells using TNFRSF21 polyclonal antibody (Cat # PAB13779). Asterisks (*) represent N-glycosylated forms and arrow shows unglycosylated form of TNFRSF21.Immunohistochemistry
Immunocytochemistry
Immunocytochemical analysis of transfected human TNFRSF21 in HEK 293 cells using TNFRSF21 polyclonal antibody (Cat # PAB13779). Confocal microscopy shows membrane localization of TNFRSF21 (nuclei stained was with anti-DRAQ5). -
Gene Info — TNFRSF21
Entrez GeneID
27242Gene Name
TNFRSF21
Gene Alias
BM-018, DR6, MGC31965
Gene Description
tumor necrosis factor receptor superfamily, member 21
Omim ID
605732Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq
Other Designations
OTTHUMP00000016561|OTTHUMP00000039915|TNFR-related death receptor 6|death receptor 6
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Interactome
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