TNFRSF21 monoclonal antibody, clone Luke-1
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Flow Cytometry
HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid coding for the extracellular domain of human TNFRSF21 (thick line). Cells (5 X 105) were incubated on ice for 30 min in 50 uL FACS buffer (PBS, 5% FCS, 0.02% sodium azide) containing 1 ug/mL of TNFRSF21 monoclonal antibody, clone Luke-1 (Cat # MAB3436).
-
Specification
Product Description
Rat monoclonal antibody raised against recombinant TNFRSF21.
Immunogen
Recombinant Fc fusion protein corresponding to amino acids 42-335 of human TNFRSF21.
Host
Rat
Reactivity
Human
Specificity
Recognizes human DR6.
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Flow Cytometry
HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid coding for the extracellular domain of human TNFRSF21 (thick line). Cells (5 X 105) were incubated on ice for 30 min in 50 uL FACS buffer (PBS, 5% FCS, 0.02% sodium azide) containing 1 ug/mL of TNFRSF21 monoclonal antibody, clone Luke-1 (Cat # MAB3436). -
Gene Info — TNFRSF21
Entrez GeneID
27242Gene Name
TNFRSF21
Gene Alias
BM-018, DR6, MGC31965
Gene Description
tumor necrosis factor receptor superfamily, member 21
Omim ID
605732Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq
Other Designations
OTTHUMP00000016561|OTTHUMP00000039915|TNFR-related death receptor 6|death receptor 6
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com