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Last updated: 2016/10/23
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SPAG6 purified MaxPab rabbit polyclonal antibody (D01P)MaxPab

  • Catalog # : H00009576-D01P
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human SPAG6 protein.
  • Immunogen:
  • SPAG6 (NP_036575.1, 1 a.a. ~ 509 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SPAG6 expression in transfected 293T cell line (H00009576-T01) by SPAG6 MaxPab polyclonal antibody.

    Lane 1: SPAG6 transfected lysate(55.50 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9576
  • Gene Name:
  • SPAG6
  • Gene Alias:
  • DKFZp434I153,MGC26276,Repro-SA-1,pf16
  • Gene Description:
  • sperm associated antigen 6
  • Gene Summary:
  • The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019296,OTTHUMP00000019297,axoneme central apparatus protein,sperm flagellar protein
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