HAND2 monoclonal antibody (M01), clone 4H8
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HAND2 expression in transfected 293T cell line by HAND2 monoclonal antibody (M01), clone 4H8.
Lane 1: HAND2 transfected lysate(21.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (34.76 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HAND2.
Immunogen
HAND2 (NP_068808.1, 135 a.a. ~ 216 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.76 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HAND2 expression in transfected 293T cell line by HAND2 monoclonal antibody (M01), clone 4H8.
Lane 1: HAND2 transfected lysate(21.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — HAND2
Entrez GeneID
9464GeneBank Accession#
NM_021973Protein Accession#
NP_068808.1Gene Name
HAND2
Gene Alias
DHAND2, FLJ16260, Hed, MGC125303, MGC125304, Thing2, bHLHa26, dHand
Gene Description
heart and neural crest derivatives expressed 2
Omim ID
602407Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq
Other Designations
basic helix-loop-helix transcription factor HAND2
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Interactome
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Disease
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