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Last updated: 2016/12/4

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TSPO rabbit monoclonal antibody

  • Catalog # : H00000706-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TSPO peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TSPO is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TSPO peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 706
  • GeneBank Accession#:
  • TSPO
  • Gene Name:
  • TSPO
  • Gene Alias:
  • BZRP,DBI,IBP,MBR,PBR,PKBS,PTBR,mDRC,pk18
  • Gene Description:
  • translocator protein (18kDa)
  • Gene Summary:
  • Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028891,benzodiazepine peripheral binding site,mitochondrial benzodiazepine receptor,peripheral benzodiazepine receptor,peripheral-type benzodiazepine receptor,translocator protein
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