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Last updated: 2014/10/20
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EIF4EBP1 polyclonal antibody

  • Catalog # : PAB12947
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of EIF4EBP1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus 14 amino acids of human EIF4EBP1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (2.5-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of EIF4EBP1 in NIH/3T3 cell lysate with EIF4EBP1 polyclonal antibody (Cat # PAB12947) at (A) 2.5, (B) 5 and (C) 10 ug/mL .
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemistry of EIF4EBP1 in NIH/3T3 cells with EIF4EBP1 polyclonal antibody (Cat # PAB12947) at 2 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1978
  • Gene Name:
  • EIF4EBP1
  • Gene Alias:
  • 4E-BP1,4EBP1,BP-1,MGC4316,PHAS-I
  • Gene Description:
  • eukaryotic translation initiation factor 4E binding protein 1
  • Gene Summary:
  • This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq
  • Other Designations:
  • eIF4E-binding protein 1,phosphorylated heat- and acid-stable protein regulated by insulin 1
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