INSR recombinant monoclonal antibody, clone 83-7
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human INSR.
Antibody Species
Mouse
Immunogen
Original antibody is raised against epitope (the cysteine rich region 140 a.a. - 301 a.a.) of the extracellular domain of human INSR.
Reactivity
Human
Form
Liquid
Isotype
IgG1 kappa
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — INSR
Entrez GeneID
3643Gene Name
INSR
Gene Alias
CD220, HHF5
Gene Description
insulin receptor
Gene Ontology
HyperlinkGene Summary
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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