INSR recombinant monoclonal antibody, clone 83-14
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human INSR.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against IM-9 lymphocytes followed by purified insulin receptor.
Reactivity
Bovine, Human, Pig, Sheep
Form
Liquid
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry
Immunofluorescence
Immunohistochemistry
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometric analysis of Jurkat cells with INSR recombinant monoclonal antibody, clone 83-14 (Cat # RAB03606).
Jurkat cells were stained with unimmunized r antibody (black line) or the r chimeric version of RAB03606 (blue line) at a concentration of 10 ug/mL for 30 mins at RT. After washing the bound antibody was detected using anti-r JK (FITC-conjugate) antibody at 2 ug/mL and cells analyzed using a FACSCanto flow-cytometer. -
Gene Info — INSR
Entrez GeneID
3643Gene Name
INSR
Gene Alias
CD220, HHF5
Gene Description
insulin receptor
Gene Ontology
HyperlinkGene Summary
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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