RB1 recombinant monoclonal antibody, clone RbS807S811-D9 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of U937 cells untreated and unstained as negative control (blue) or untreated and stained (green) or treated with lambda phosphatase and stained (red) using Phospho-Rb (Ser807/811) antibody RBS807S811-D9 SureLight488 conjugate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human RB1.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser807/811 of human phospho-Rb
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells untreated and unstained as negative control (blue) or untreated and stained (green) or treated with lambda phosphatase and stained (red) using Phospho-Rb (Ser807/811) antibody RBS807S811-D9 SureLight488 conjugate. -
Gene Info — RB1
Entrez GeneID
5925Protein Accession#
P06400Gene Name
RB1
Gene Alias
OSRC, RB, p105-Rb, pRb, pp110
Gene Description
retinoblastoma 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq
Other Designations
OTTHUMP00000018397|retinoblastoma suspectibility protein|retinoblastoma-associated protein
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Interactome
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Pathway
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Disease
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