Anti-EPCAM monoclonal antibody (Biotin)
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Specification
Product Description
Anti-EPCAM monoclonal antibody (Biotin) is a biotin-conjugated monoclonal antibody for identification of cells expressing the EPCAM antigen.
Immunogen
EPCAM (NP_002345.1, 24 a.a. ~ 265 a.a) recombinant protein with His-FLAG-Strep II tag.
Clone Name
2F10
Host
Mouse
Specificity
This antibody reacts with human EpCAM.
Conjugation
Biotin
Isotype
IgG1, kappa
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at 2-8°C.
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Applications
Immunofluorescence
Immunofluorescence staining on SK-BR-3 cells using Anti-EPCAM monoclonal antibody (Biotin) and FITC conjugated secondary antibody shows positive result. -
Gene Info — EPCAM
Entrez GeneID
4072Gene Name
EPCAM
Gene Alias
17-1A, 323/A3, CD326, CO-17A, CO17-1A, EGP, EGP-2, EGP34, EGP40, ESA, Ep-CAM, GA733-2, HEA125, KS1/4, KSA, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1, hEGP-2
Gene Description
epithelial cell adhesion molecule
Omim ID
185535Gene Ontology
HyperlinkGene Summary
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq
Other Designations
adenocarcinoma-associated antigen|carcinoma-associated antigen GA733-2|human epithelial glycoprotein-2|membrane component, chromosome 4, surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1
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Interactome
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