ADRBK1 monoclonal antibody, clone EGE-1
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of THP-1 cell lysate with ADRBK1 monoclonal antibody, clone EGE-1 (Cat # MAB20106).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human ADRBK1.
Immunogen
A synthetic peptide corresponding to human ADRBK1.
Host
Rabbit
Theoretical MW (kDa)
79.574
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of THP-1 cell lysate with ADRBK1 monoclonal antibody, clone EGE-1 (Cat # MAB20106).Immunohistochemistry
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Gene Info — ADRBK1
Entrez GeneID
156Protein Accession#
P25098Gene Name
ADRBK1
Gene Alias
BARK1, BETA-ARK1, FLJ16718, GRK2
Gene Description
adrenergic, beta, receptor kinase 1
Omim ID
109635Gene Ontology
HyperlinkGene Summary
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq
Other Designations
beta adrenergic receptor kinase 1
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Interactome
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Pathway
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Disease
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