SLC6A4 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
SLC6A4 MaxPab rabbit polyclonal antibody. Western Blot analysis of SLC6A4 expression in mouse lung.
Western Blot (Transfected lysate)
Western Blot analysis of SLC6A4 expression in transfected 293T cell line (H00006532-T01) by SLC6A4 MaxPab polyclonal antibody.
Lane 1: SLC6A4 transfected lysate(70.30 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SLC6A4 protein.
Immunogen
SLC6A4 (AAH69484.1, 1 a.a. ~ 630 a.a) full-length human protein.
Sequence
METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SLC6A4 MaxPab rabbit polyclonal antibody. Western Blot analysis of SLC6A4 expression in mouse lung.Western Blot (Transfected lysate)
Western Blot analysis of SLC6A4 expression in transfected 293T cell line (H00006532-T01) by SLC6A4 MaxPab polyclonal antibody.
Lane 1: SLC6A4 transfected lysate(70.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SLC6A4
Entrez GeneID
6532GeneBank Accession#
NM_001045.2Protein Accession#
AAH69484.1Gene Name
SLC6A4
Gene Alias
5-HTT, 5HTT, HTT, OCD1, SERT, hSERT
Gene Description
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
Other Designations
5-hydroxytryptamine transporter|5HT transporter|Na+/Cl- dependent serotonin transporter|serotonin transporter|sodium-dependent serotonin transporter|solute carrier family 6 member 4
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Interactome
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Disease
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