SLC6A4 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SLC6A4.
Immunogen
SLC6A4 (NP_001036, 181 a.a. ~ 252 a.a) partial recombinant protein with GST tag.
Sequence
AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGIS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.03 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SLC6A4
Entrez GeneID
6532GeneBank Accession#
NM_001045Protein Accession#
NP_001036Gene Name
SLC6A4
Gene Alias
5-HTT, 5HTT, HTT, OCD1, SERT, hSERT
Gene Description
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
Other Designations
5-hydroxytryptamine transporter|5HT transporter|Na+/Cl- dependent serotonin transporter|serotonin transporter|sodium-dependent serotonin transporter|solute carrier family 6 member 4
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Interactome
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Disease
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