SLC6A4 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SLC6A4 full-length
Host
Human
Theoretical MW (kDa)
70.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SLC6A4 antibody (H00006532-B01) by Western Blots.
SDS-PAGE Gel
SLC6A4 transfected lysate.
Western Blot
Lane 1: SLC6A4 transfected lysate ( 70.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SLC6A4
Entrez GeneID
6532GeneBank Accession#
NM_001045.2Protein Accession#
-Gene Name
SLC6A4
Gene Alias
5-HTT, 5HTT, HTT, OCD1, SERT, hSERT
Gene Description
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
Other Designations
5-hydroxytryptamine transporter|5HT transporter|Na+/Cl- dependent serotonin transporter|serotonin transporter|sodium-dependent serotonin transporter|solute carrier family 6 member 4
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Interactome
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Disease
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