OPA1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Western Blot (Tissue lysate)
OPA1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OPA1 expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of OPA1 expression in transfected 293T cell line (H00004976-T01) by OPA1 MaxPab polyclonal antibody.
Lane 1: OPA1 transfected lysate(111.60 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human OPA1 protein.
Immunogen
OPA1 (NP_056375.1, 1 a.a. ~ 960 a.a) full-length human protein.
Sequence
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
OPA1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OPA1 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of OPA1 expression in transfected 293T cell line (H00004976-T01) by OPA1 MaxPab polyclonal antibody.
Lane 1: OPA1 transfected lysate(111.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — OPA1
Entrez GeneID
4976GeneBank Accession#
NM_015560Protein Accession#
NP_056375.1Gene Name
OPA1
Gene Alias
FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Gene Description
optic atrophy 1 (autosomal dominant)
Gene Ontology
HyperlinkGene Summary
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000195065|mitochondrial dynamin-like GTPase|optic atrophy 1
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Interactome
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Disease
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