OPA1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
OPA1 transfected lysate.
Western Blot
Lane 1: OPA1 transfected lysate ( 111.6 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-OPA1 full-length
Host
Human
Theoretical MW (kDa)
111.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-OPA1 antibody (H00004976-B01) by Western Blots.
SDS-PAGE Gel
OPA1 transfected lysate.
Western Blot
Lane 1: OPA1 transfected lysate ( 111.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — OPA1
Entrez GeneID
4976GeneBank Accession#
NM_015560Protein Accession#
NP_056375Gene Name
OPA1
Gene Alias
FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Gene Description
optic atrophy 1 (autosomal dominant)
Gene Ontology
HyperlinkGene Summary
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000195065|mitochondrial dynamin-like GTPase|optic atrophy 1
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Interactome
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Disease
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