CCR5 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and CCR5 expressing 293 cells (Green) using CCR5 purified MaxPab mouse polyclonal antibody.
Western Blot (Cell lysate)
CCR5 MaxPab polyclonal antibody. Western Blot analysis of CCR5 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of CCR5 expression in transfected 293T cell line (H00001234-T01) by CCR5 MaxPab polyclonal antibody.
Lane 1: CCR5 transfected lysate(40.05 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CCR5 protein.
Immunogen
CCR5 (XP_001125981.1, 1 a.a. ~ 352 a.a) full-length human protein.
Sequence
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and CCR5 expressing 293 cells (Green) using CCR5 purified MaxPab mouse polyclonal antibody.Western Blot (Cell lysate)
CCR5 MaxPab polyclonal antibody. Western Blot analysis of CCR5 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of CCR5 expression in transfected 293T cell line (H00001234-T01) by CCR5 MaxPab polyclonal antibody.
Lane 1: CCR5 transfected lysate(40.05 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CCR5
Entrez GeneID
1234GeneBank Accession#
NM_000579Protein Accession#
XP_001125981.1Gene Name
CCR5
Gene Alias
CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Gene Description
chemokine (C-C motif) receptor 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
C-C chemokine receptor 5|C-C chemokine receptor type 5|CCR5 chemokine receptor|chemokine (C-C) receptor 5|chemokine receptor CCR5|chemr13
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Interactome
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Pathway
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Disease
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