A2M polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with A2M polyclonal antibody (PAB28545).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with A2M polyclonal antibody (Cat # PAB28545) shows moderate cytoplasmic positivity in hepatocytes.
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant A2M.
Immunogen
Recombinant protein corresponding to amino acids of recombinant A2M.
Sequence
SVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:200-1:500)
Western Blot(-)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with A2M polyclonal antibody (PAB28545).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with A2M polyclonal antibody (Cat # PAB28545) shows moderate cytoplasmic positivity in hepatocytes. -
Gene Info — A2M
Entrez GeneID
2Protein Accession#
P01023Gene Name
A2M
Gene Alias
CPAMD5, DKFZp779B086, FWP007, S863-7
Gene Description
alpha-2-macroglobulin
Gene Ontology
HyperlinkGene Summary
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations
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Interactomes
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Pathways
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Diseases
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