SOD1 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against SOD1.
Immunogen
Human SOD1 (Cu/Zn Superoxide dismutase).
Host
Rabbit
Reactivity
Bovine, Dog, Frog, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Specificity
This antibody detects a 23 KDa protein in human (and a 19 KDa protein in other species) on SDS-PAGE immunoblots, corresponding to the molecular mass of Cu/Zn SOD.
Form
Liquid
Recommend Usage
Western Blot (0.2 ug/mL)
Immunohistochemistry (1 ug/mL)
Immunoprecipitation (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.0 (50% glycerol, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SOD1
Entrez GeneID
6647Gene Name
SOD1
Gene Alias
ALS, ALS1, IPOA, SOD, homodimer
Gene Description
superoxide dismutase 1, soluble
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
Other Designations
Cu /Zn superoxide dismutase|Cu/Zn superoxide dismutase|SOD, soluble|indophenoloxidase A|superoxide dismutase, cystolic
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Interactomes
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Pathways
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