Histone H2A type 1-B/E (hydroxyl Y39) monoclonal antibody, clone 3B12
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of mouse spleen tissue with Histone H2A type 1-B/E (hydroxyl Y39) monoclonal antibody, clone 3B12 (Cat # RAB04188).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Histone H2A type 1-B/E.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic hydroxyl peptide corresponding to residues surrounding Y39 of human histone H2A type 1-B/E.
Theoretical MW (kDa)
Calculated MW: 14 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse spleen tissue with Histone H2A type 1-B/E (hydroxyl Y39) monoclonal antibody, clone 3B12 (Cat # RAB04188).Enzyme-linked Immunoabsorbent Assay
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Gene Info — HIST1H2AB
Entrez GeneID
8335Protein Accession#
P04908Gene Name
HIST1H2AB
Gene Alias
H2A/m, H2AFM
Gene Description
histone cluster 1, H2ab
Omim ID
602795Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq
Other Designations
H2A histone family, member M|OTTHUMP00000016137|histone 1, H2ab
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Interactome
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Disease
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