Recombinant rabbit monoclonal antibody raised against human CD99.
Original antibody is raised against recombinant protein corresponding to full length human MIC2.
Recognizes a sialoglycoprotein of 27-32kDa which identified as CD99.
Protein A purification
Flow Cytometry (2-4 ug/million cells) Immunofluorescence (2-4 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
CD99 antigen,E2 antigen,MIC2 (monoclonal antibody 12E7),OTTHUMP00000022840,T-cell surface glycoprotein E2,antigen identified by monoclonal 12E7, Y homolog,antigen identified by monoclonal antibodies 12E7, F21 and O13,surface antigen MIC2