GLI3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GLI3.
Immunogen
A synthetic peptide corresponding to human GLI3.
Sequence
C-HNKRSKIKPDED
Host
Goat
Theoretical MW (kDa)
170
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — GLI3
Entrez GeneID
2737Protein Accession#
NP_000159.2Gene Name
GLI3
Gene Alias
ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
Gene Description
GLI-Kruppel family member GLI3
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq
Other Designations
DNA-binding protein|OTTHUMP00000025248|OTTHUMP00000159085|oncogene GLI3|zinc finger protein GLI3
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK.
PLoS Genetics 2005 Oct; 1(4):e53.
Application：IF, IHC-Fr, WB, Mouse, Mouse embryos, Primary limb cell cultures.
-
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com