GLI3 polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
GLI3 polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of GLI3 expression in HL-60 ( Cat # L014V1 ).
Western Blot detection against Immunogen (38.21 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant GLI3.
Immunogen
GLI3 (NP_000159, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
Sequence
MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GLI3 polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of GLI3 expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — GLI3
Entrez GeneID
2737GeneBank Accession#
NM_000168Protein Accession#
NP_000159Gene Name
GLI3
Gene Alias
ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
Gene Description
GLI-Kruppel family member GLI3
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq
Other Designations
DNA-binding protein|OTTHUMP00000025248|OTTHUMP00000159085|oncogene GLI3|zinc finger protein GLI3
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Interactome
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Pathway
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Disease
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