DUOX1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with DUOX1 polyclonal antibody (Cat # PAB30938) shows strong cytoplasmic positivity in parietal cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human DUOX1.
Immunogen
Recombinant protein corresponding to human DUOX1.
Sequence
QHKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with DUOX1 polyclonal antibody (Cat # PAB30938) shows strong cytoplasmic positivity in parietal cells. -
Gene Info — DUOX1
Entrez GeneID
53905Protein Accession#
Q9NRD9Gene Name
DUOX1
Gene Alias
LNOX1, MGC138840, MGC138841, NOXEF1, THOX1
Gene Description
dual oxidase 1
Omim ID
606758Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
Other Designations
NADPH thyroid oxidase 1|flavoprotein NADPH oxidase|nicotinamide adenine dinucleotide phosphate oxidase
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Interactome
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Disease
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