Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast carcinoma tissue with MYB (phospho S532) polyclonal antibody (Cat # PAB29583) under 1:50-1:100 dilution (A) or treated with synthesized peptide (B).
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq