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Last updated: 2016/12/4

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NRAS polyclonal antibody

  • Catalog # : PAB27439
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NRAS.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids at C-terminus of human NRAS.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • NRAS antibody is predicted to not cross-react with H-RAS
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of NRAS in 293 cell lysate with NRAS polyclonal antibody (Cat # PAB27439) at (lane 1) 1 and (lane 2) 2 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4893
  • Gene Name:
  • NRAS
  • Gene Alias:
  • ALPS4,N-ras,NRAS1
  • Gene Description:
  • neuroblastoma RAS viral (v-ras) oncogene homolog
  • Gene Summary:
  • This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). [provided by RefSeq
  • Other Designations:
  • N-ras protein part 4,OTTHUMP00000013879,v-ras neuroblastoma RAS viral oncogene homolog
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