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Last updated: 2016/12/4
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SIPA1 polyclonal antibody

  • Catalog # : PAB25780
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SIPA1.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acids at N-terminus of human SIPA1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunofluorescence (20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of SIPA1 in human brain tissue with SIPA1 polyclonal antibody (Cat # PAB25780) at 1 ug/mL.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of SIPA1 in human brain with SIPA1 polyclonal antibody (Cat # PAB25780) at 20 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6494
  • Gene Name:
  • SIPA1
  • Gene Alias:
  • MGC102688,MGC17037,SPA1
  • Gene Description:
  • signal-induced proliferation-associated 1
  • Gene Summary:
  • The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq
  • Other Designations:
  • GTPase-activating protein Spa-1,p130 SPA-1,signal-induced proliferation-associated gene 1,signal-induced proliferation-associated protein 1
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